USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: Q12846 USC-OGP 2-DE database:  Q12846 Q12846 General information about the entry View entry in simple text format Entry name STX4_HUMAN Primary accession number Q12846 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Syntaxin-4; AltName: Full=Renal carcinoma antigen NY-REN-31;. Gene name Name=STX4 Synonyms=STX4A Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0754: pI=5.17; Mw=32801 Cross-references UniProtKB/Swiss-Prot Q12846; STX4_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name STX4_HUMAN Primary accession number Q12846 Secondary accession number(s) A8MXY0 Q15525 Q6FHE8 Sequence was last modified on  July 15, 1998 (version 2) Annotations were last modified on  March 15, 2017 (version 164) Name and origin of the protein Description RecName: Full=Syntaxin-4; AltName: Full=Renal carcinoma antigen NY-REN-31; Gene name Name=STX4 Synonyms=STX4A Encoded on Name=STX4; Synonyms=STX4A Keywords Alternative splicing; Cell membrane; Coiled coil; Complete proteome; Membrane; Neurotransmitter transport; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U07158; AAA20967.1; -; mRNA EMBL X85784; CAA59769.1; -; mRNA EMBL AJ000541; CAA04174.1; -; mRNA EMBL AF026007; AAB88810.1; -; mRNA EMBL AF318489; AAG40313.1; -; Transcribed_RNA EMBL BT007326; AAP35990.1; -; mRNA EMBL AK091833; BAG52424.1; -; mRNA EMBL AK315716; BAG38075.1; -; mRNA EMBL CR541806; CAG46605.1; -; mRNA EMBL AC135050; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471192; EAW52176.1; -; Genomic_DNA EMBL CH471192; EAW52177.1; -; Genomic_DNA EMBL BC002436; AAH02436.1; -; mRNA CCDS CCDS10700.1; -. [Q12846-1]; . CCDS CCDS61916.1; -. [Q12846-2]; . PIR I38517; I38517; . PIR S52726; S52726; . RefSeq NP_001259025.1; NM_001272096.1. [Q12846-2]; . RefSeq NP_004595.2; NM_004604.4. [Q12846-1]; . UniGene Hs.83734; -; . ProteinModelPortal Q12846; -; . SMR Q12846; -; . BioGrid 112679; 64; . IntAct Q12846; 49; . MINT MINT-1454763; -; . STRING 9606.ENSP00000317714; -; . TCDB 1.F.1.1.1; the synaptosomal vesicle fusion pore (svf-pore) family; . iPTMnet Q12846; -; . PhosphoSitePlus Q12846; -; . SwissPalm Q12846; -; . DMDM 3041737; -; . OGP Q12846; -; . EPD Q12846; -; . MaxQB Q12846; -; . PaxDb Q12846; -; . PeptideAtlas Q12846; -; . PRIDE Q12846; -; . DNASU 6810; -; . Ensembl ENST00000313843; ENSP00000317714; ENSG00000103496. [Q12846-1]; . Ensembl ENST00000394998; ENSP00000378447; ENSG00000103496. [Q12846-2]; . GeneID 6810; -; . KEGG hsa:6810; -; . UCSC uc002eak.5; human. [Q12846-1]; . CTD 6810; -; . DisGeNET 6810; -; . GeneCards STX4; -; . HGNC HGNC:11439; STX4; . HPA HPA001330; -; . MIM 186591; gene; . neXtProt NX_Q12846; -; . OpenTargets ENSG00000103496; -; . PharmGKB PA36236; -; . eggNOG KOG0810; Eukaryota; . eggNOG COG5074; LUCA; . GeneTree ENSGT00760000119200; -; . HOGENOM HOG000286023; -; . HOVERGEN HBG000497; -; . InParanoid Q12846; -; . KO K13502; -; . OMA YEMSNIN; -; . OrthoDB EOG091G0EUK; -; . PhylomeDB Q12846; -; . TreeFam TF313763; -; . Reactome R-HSA-114516; Disinhibition of SNARE formation; . Reactome R-HSA-1236974; ER-Phagosome pathway; . Reactome R-HSA-1445148; Translocation of GLUT4 to the plasma membrane; . Reactome R-HSA-421837; Clathrin derived vesicle budding; . Reactome R-HSA-449147; Signaling by Interleukins; . ChiTaRS STX4; human; . GeneWiki STX4; -; . GenomeRNAi 6810; -; . PRO PR:Q12846; -; . Proteomes UP000005640; Chromosome 16; . Bgee ENSG00000103496; -; . CleanEx HS_STX4; -; . ExpressionAtlas Q12846; baseline and differential; . Genevisible Q12846; HS; . GO GO:0016323; C:basolateral plasma membrane; IDA:HGNC; . GO GO:0009986; C:cell surface; IDA:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0043197; C:dendritic spine; IDA:UniProtKB; . GO GO:0005768; C:endosome; IDA:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005615; C:extracellular space; IDA:UniProtKB; . GO GO:0016021; C:integral component of membrane; IBA:GO_Central; . GO GO:0005622; C:intracellular; IDA:UniProtKB; . GO GO:0030027; C:lamellipodium; IDA:UniProtKB; . GO GO:0043219; C:lateral loop; IEA:Ensembl; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0035749; C:myelin sheath adaxonal region; IEA:Ensembl; . GO GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl; . GO GO:0030670; C:phagocytic vesicle membrane; TAS:Reactome; . GO GO:0005886; C:plasma membrane; IDA:UniProtKB; . GO GO:0031201; C:SNARE complex; IDA:UniProtKB; . GO GO:0036477; C:somatodendritic compartment; IDA:UniProtKB; . GO GO:0042581; C:specific granule; IDA:UniProtKB; . GO GO:0000322; C:storage vacuole; IEA:Ensembl; . GO GO:0045202; C:synapse; IDA:UniProtKB; . GO GO:0008021; C:synaptic vesicle; IBA:GO_Central; . GO GO:0005802; C:trans-Golgi network; IEA:Ensembl; . GO GO:0005773; C:vacuole; TAS:HGNC; . GO GO:0005484; F:SNAP receptor activity; IBA:GO_Central; . GO GO:0000149; F:SNARE binding; IBA:GO_Central; . GO GO:0016230; F:sphingomyelin phosphodiesterase activator activity; IMP:UniProtKB; . GO GO:0006886; P:intracellular protein transport; IBA:GO_Central; . GO GO:0060291; P:long-term synaptic potentiation; IDA:UniProtKB; . GO GO:0048284; P:organelle fusion; IDA:UniProtKB; . GO GO:0043085; P:positive regulation of catalytic activity; IMP:UniProtKB; . GO GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB; . GO GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB; . GO GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB; . GO GO:0050921; P:positive regulation of chemotaxis; IMP:UniProtKB; . GO GO:0043311; P:positive regulation of eosinophil degranulation; IMP:UniProtKB; . GO GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IMP:UniProtKB; . GO GO:0051024; P:positive regulation of immunoglobulin secretion; IMP:UniProtKB; . GO GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IDA:UniProtKB; . GO GO:2000010; P:positive regulation of protein localization to cell surface; IMP:UniProtKB; . GO GO:1903078; P:positive regulation of protein localization to plasma membrane; IMP:UniProtKB; . GO GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome; . GO GO:0017157; P:regulation of exocytosis; IMP:UniProtKB; . GO GO:1902041; P:regulation of extrinsic apoptotic signaling pathway via death domain receptors; IMP:UniProtKB; . GO GO:0033194; P:response to hydroperoxide; IDA:UniProtKB; . GO GO:0035493; P:SNARE complex assembly; IEA:Ensembl; . GO GO:0031629; P:synaptic vesicle fusion to presynaptic active zone membrane; IBA:GO_Central; . GO GO:0048278; P:vesicle docking; IBA:GO_Central; . GO GO:1990668; P:vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane; TAS:Reactome; . InterPro IPR010989; SNARE; . InterPro IPR006012; Syntaxin/epimorphin_CS; . InterPro IPR006011; Syntaxin_N; . InterPro IPR000727; T_SNARE_dom; . Pfam PF05739; SNARE; 1; . Pfam PF00804; Syntaxin; 1; . SMART SM00503; SynN; 1; . SMART SM00397; t_SNARE; 1; . SUPFAM SSF47661; SSF47661; 1; . PROSITE PS00914; SYNTAXIN; 1; . PROSITE PS50192; T_SNARE; 1; .

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